After much persuasion by his friends a twenty-year-old university student took 150 micrograms of LSD It was an "interesting but disturbing time. " Thereafter it became very difficult for him to study or concentrate, and he decided to drop out of school. He was unable to continue his part-time job as a stock clerk. There were strong feelings of the meaninglessness of life and he said that he was "philosophically confused." Some days he felt normal again for a few hours, but then the strange, moving, compressing walls and time standing still made him fear he was going crazy. He had occasional thoughts of self-destruction. He would become very upset and panicky, break out into a sweat and sometimes freeze in terror. With considerable support, strong reassurance and tranquilizer therapy, the condition subsided six months after the LSD session (Cohen, 1970 [1965], p. 92).Because of inadequate reporting and problems in interpreting symptoms and causes, it is hard to tell how common adverse reactions are. At Bellevue Hospital in New York from early 1965 to 1967, 200 patients appeared with complaints related to LSDmostly panic reactions and flashbacks (Frosch, 1969). By 1969 Bellevue was seeing only one LSD reaction every 2 weeks, and most of these were thought to be borderline schizophrenics in whom the drug had precipitated a psychosis (Stern & Robbins, 1969). A 1971 Canadian government survey of the hospital records of 22,885 psychiatric patients found 67 cases (0.3 percent) where LSD was mentioned as a factor in the primary diagnosis; most of these patients had used many drugs, and the precise influence of LSD was often unclear (Final Report, 1973, p. 378).
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